Correlation of Intraoperative Optical Coherence Tomography of Crystalline Lens Diameter, Thickness, and Volume with Biometry and Age

PurposeTo characterize crystalline lens dimensions derived from in vivo spectral-domain optical coherence tomography (SD-OCT) and identify associations among these parameters, ocular biometry, age.MethodsIn this retrospective study, thickness (LT), diameter (LD), volume (LV) were measured intraoperatively using SD-OCT 293 eyes undergoing surgery. Correlations LT, LD, LV, age, axial length (AL), anterior chamber depth (ACD) analyzed. Multiple regression analysis was performed to determine whether a combination of biometric data could predict LD LV.ResultsWide variations observed LT (3.6-5.7 mm), (7.5-11.9 LV (119.9-312.4 mm3) aging eyes. the 3 statistically significant (LV-LT: r = 0.785; P < .001; LV-LD: 0.696; LT-LD: 0.121; .039). With correlation coefficients 0.526, 0.326, 0.573, respectively (P .001). Although there AL with (r −0.137; .002) 0.268; .001), it not 0.084; .15). Subgroup revealed that 19.8% long had >1 standard deviation (SD) above 5.2% <1 SD below mean LD.ConclusionsDimensions vary considerably are most accurately characterized by direct measurement rather than making assumptions based on AL. These findings challenge historically proposed relationships between represent normative dataset contemporary geometric features lens, possibly aiding surgical decision future developments To age. In LV. Wide LD. Dimensions